EFFECT OF BIOLOGICAL SEX AND SHORT-TERM HIGH-FAT DIET ON CELLULAR PROLIFERATION, RIBOSOMAL BIOGENESIS, AND TARGETED PROTEIN ABUNDANCE IN MURINE ARTICULAR CARTILAGE

Effect of biological sex and short-term high-fat diet on cellular proliferation, ribosomal biogenesis, and targeted protein abundance in murine articular cartilage

Objective: To identify factors contributing to sex-differences in OA risk by evaluating the short-term effect of high-fat (HF) diet on envox stock sex-specific changes in cartilage cell proliferation, ribosomal biogenesis, and targeted extra-cellular and cellular protein abundance.Materials and methods: Knee cartilage was harvested to the subchondr

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Hypoxia-responsive nanoreactors based on self-enhanced photodynamic sensitization and triggered ferroptosis for cancer synergistic therapy

Abstract Background Photodynamic therapy (PDT), a typical reactive oxygen species (ROS)-dependent treatment with high controllability, has emerged as an alternative cancer therapy modality but its therapeutic efficacy is still unsatisfactory due to the limited light penetration and constant oxygen consumption.With the development of another ROS-dep

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Taxonomy of the ant genus Nesomyrmex Wheeler (Formicidae, Myrmicinae) in the Afrotropical region, with a review of current species groups and description of a new species of the N. angulatus group from Mozambique

This study reviews the taxonomy of the ant genus Nesomyrmex Wheeler, 1910 in the Afrotropical region.Previous revisionary studies are discussed and four species groups are proposed on the basis of external morphology.The N.angulatus group contains seven species that are widely distributed throughout the whole Afrotropical region, with one species a

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